Antifungals
Antifungals are primarily used to combat infections in immunocompromised individuals and post-transplantation. There are few targets and chemical classes with three types of antifungal currently in clinical use, polyenes, triazoles, and echinocandins, agents that alter membrane function, cell wall structure and DNA and protein synthesis. Most antifungal agents are not completely effective due to the development of resistance, toxicity and side effects that limit their use and new resistance patterns have emerged including simultaneous resistance to different antifungal classes.
Antimicrobial peptides
| Cat No. | Product Name | Activity |
|---|---|---|
| AM-160 | Bac2A | Broad spectrum antimicrobial |
| AM-030 | BMAP 28 (bovine) | Bovine myeloid cathelicidin with activitiy against bacteria and fungi |
| AM-080 | Cecropin A | Broad spectrum insect antimicrobial |
| AM-081 | Cecropin B | Broad spectrum insect antimicrobial peptide |
| AM-090 | Histatin 3 | Antimicrobial peptide found in saliva |
| AM-091 | Histatin 5 | Antimicrobial peptide found in saliva |
| AM-092 | Histatin 8 | Antimicrobial peptide found in saliva |
| AM-070 | Indolicidin | Cathelicidin family antimicrobial peptide |
| AM-005 | LL 37 (13–37) (human) | Broad spectrum antimicrobial |
| AM-006 | LL 37 (18-37) (human) | Broad spectrum antimicrobial |
| AM-400 | PGLa | Antimicrobial peptide |
| AM-140 | RsAFP2 | Antifungal plant defensin isolated from radish seeds |
| AM-151 | RW2 | Antimicrobial and antifungal |
| AM-150 | RW3 | Antimicrobial and antifungal |
| AM-152 | RW4 | Antimicrobial and antifungal |
| AM-020 | SMAP 29 (sheep) | Broad spectrum antimicrobial |
| AM-410 | Thanatin | Binds to E. Coli LptA and LptD |
Cell penetrating peptides
| Cat No. | Product Name | Activity |
|---|---|---|
| AM-120 | (Arg)9 | Cell penetrating peptide |
Peptides
| Cat No. | Product Name | Activity |
|---|---|---|
| AM-390 | Candidalysin | Fungal cytolytic peptide toxin from Candida albicans |
Peptoids
| Cat No. | Product Name | Activity |
|---|---|---|
| PT-109 | AEC5 | Lipopeptoid with antifungal activity against Cryptococcus neoformans |
| PT-110 | β-5 | Lipopeptoid with antifungal activity |
| PT-120 | γ-2 | Lipopeptoid with antifungal activity |
Further reading
Ghannoum and Rice (1999) Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin. Microbiol. Rev. 12(4) 501 PMID: 10515900
Campoy and Adrio (2017) Antifungals, Biochemical Pharmacology 133 86 PMID: 27884742
Perlin (2017) Antifungals. In: Prasad R. (eds) Candida albicans: Cellular and Molecular Biology. Springer, Cham. https://doi.org/10.1007/978-3-319-50409-4_22
Bilal et al (2025) Fungal Influences on Cancer Initiation, Progression, and Response to Treatment. Cancer Res 85 3) 413 https://doi.org/10.1158/0008-5472.CAN-24-1609
Related Targets
Contact Information
To place an order, or for customer services, order processing or technical support please contact us on:
UK, Europe and RoW
Tel: (+44) 01392 422205
Fax: (+44) 01392 279510
info@iscabiochemicals.com
USA and Canada
Tel: 610-994-1134
Toll Free: 855-FOCUS21 (855-362-8721)
Fax: 610-465-9100
France
CliniSciences
Tel : +33 9 77 40 09 09
Fax : +33 9 77 40 10 11
Orders and customer support : info@clinisciences.com
Germany, Switzerland, Austria
BIOZOL Diagnostics
Tel: +49 (089) 3799 666-6
Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: info@biozol.de
Italy
Labospace
Tel: +39 02 35980841
Fax +39 02 359808004
Orders: info@labospace.com
Spain and Portugal
Abyntek Biopharma
Tel: +34 94 404 80 80
Fax: +34 94 404 80 81
Orders: info@abyntek.com
BIOHUB INTERNATIONAL
上海起发实验试剂有限公司
Tel: +86-15921799099
Tel: +86-021-50724187
Fax: +86-021-50724961
Orders: sale3@78bio.com
India
BTL Biotechno Labs Pvt Ltd
Tel: +91-8860924629
07291852429
Orders, Technical and Customer support: info@biotechnolabs.com
Japan
Namiki Shoji Co.
Tel：+81-050-5527-9850
Fax：+81-3-3352-2196
email: globalbusiness1@namiki-s.co.jp