Search
0
Items
Select
Search
MENU
Select

Antivirals

Antivirals are agents with the ability to either prevent viral infections or inhibit virus replication.   Many antiviral agents act on the key proteins involved in host-cell machinery although antivirals also target viral entry and modulation of the cellular defence system.  Some antivirals target components of the host cell and alter the ability of the virus to replicate efficiently, while others bind to the viral polymerase complex and restrict viral replication.   Mechanisms of antiviral action include entry inhibitors of transcription, viral ribonuclease H, HBV surface antigen secretion, viral protease, RNA-dependent RNA polymerase, reverse transcriptase, viral neuraminidase, integrase strand transfer, DNA polymerase inhibitor and modulators of viral capsid assembly.
Antimicrobial peptides
Cat No. Product Name Activity
AM-420 Epinecidin-1 Antimicrobial peptide from orange-spotted grouper
AM-380 Hc-CATH

Cathelicidin from sea snake venom

AM-070 Indolicidin Cathelicidin family antimicrobial peptide
AM-005 LL 37 (13–37) (human) Broad spectrum antimicrobial
AM-001 LL 37 (human) Host defence peptide derived from the C-terminal of human cathelicidin antimicrobial peptide
AM-100 Magainin 1 Broad spectrum antimicrobial 
AM-101 Magainin 2 Broad spectrum antimicrobial
AM-040 mCRAMP (mouse) Sole murine cathelicidin and homologue of human LL 37
CV-060 P9R Defensin like peptide with potent antiviral activity
AM-400 PGLa Antimicrobial peptide
AM-350 Urumin Antiviral host defense peptide
Cell penetrating peptides
Cat No. Product Name Activity
CP-020 TAT 2-4 Cell-penetrating dimer of the protein transduction domain (47-58) of HIV-tat
PP-200 Tat-beclin 1 Autophagy inducing peptide
Fluorescent labelled peptides
Cat No. Product Name Activity
CV-070 MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro)
Peptides
Cat No. Product Name Activity
IG-010 A20FMDV2 Selective alpha-v beta-6 (αvβ6) integrin antagonist
OP-010 Decanoyl-RVKR-CMK Proprotein convertase inhibitor
CK-030 EPI-X4 Endogenous CXCR4 antagonist
AV-010 F9170 Inactivates HIV-1 virions 
AM-190 LAP Inhibits viral IRES mediated translation
CV-050 SBP1 Binds to the SARS-CoV-2 receptor binding domain
EP-020 SFKEELDKYFKNHTSP Epitope from the S2 protein of SARS-CoV-2
PP-450 T2857W KIX–MLL interaction inhibitor
AV-020 VIRIP Endogenous HIV-1 inhibitor
Small molecules
Cat No. Product Name Activity
CK-060 Maraviroc CCR5 antagonist
CV-030 N4-Hydroxycytidine Broad spectrum antiviral
CV-040 Nelfinavir mesylate Human immunodeficiency virus (HIV)-1 protease inhibitor

Further reading

Paintsil and Cheng (2009) Antiviral Agents. Encyclopedia of Microbiology 223 PMC7149689

De Clercq and Li (2016) Approved Antiviral Drugs over the Past 50 Years Clinical Microbiology Reviews 29(3) 695 PMID: 27281742

Andersen et al (2020) Discovery and development of safe-in-man broad-spectrum antiviral agents. Int. J. Infectious Diseases 93 268 PMID: 32081774

Kausar et al (2021) A review: Mechanism of action of antiviral drugs. Int J Immunopathol Pharmacol. 35 20587384211002621 PMID: 33726557

Contact Information

To place an order, or for customer services, order processing or technical support please contact us on:

UK, Europe and RoW
Tel: (+44) 01392 422205
Fax: (+44) 01392 279510
info@iscabiochemicals.com

USA and Canada

Tel: 610-994-1134

Toll Free: 855-FOCUS21 (855-362-8721)

Fax: 610-465-9100

sales@focusbiomolecules.com 


France

CliniSciences
Tel : +33 9 77 40 09 09
Fax :  +33 9 77 40 10 11
Orders and customer support : info@clinisciences.com


Germany, Switzerland, Austria

BIOZOL Diagnostics 

Tel: +49 (089) 3799 666-6

Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: info@biozol.de


Italy
Labospace
Tel: +39 02 35980841
Fax +39 02 359808004
Orders: info@labospace.com


Spain and Portugal
Abyntek Biopharma
Tel: +34 94 404 80 80

Fax: +34 94 404 80 81
Orders: info@abyntek.com


China

BIOHUB INTERNATIONAL 

上海起发实验试剂有限公司

Tel: +86-15921799099

Tel: +86-021-50724187

Fax: +86-021-50724961

Orders: sale3@78bio.com

India
BTL Biotechno Labs Pvt Ltd
Tel: +91-8860924629
07291852429
Orders, Technical and Customer support: info@biotechnolabs.com


Japan

Namiki Shoji Co.
Tel:+81-050-5527-9850
Fax:+81-3-3352-2196
email:  globalbusiness1@namiki-s.co.jp


All distributors >