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(Arg)9
Cat. No. AM-120
Structure:
H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH
Other Names:
Nonaarginine, Nona-L-arginine, Peptide R9
Activity:
Cell penetrating peptide
(Arg)9, also known as nonaarginine, is a a cationic cell penetrating peptide (CPP) consisting of 9 arginines. Arginine-rich cell-penetrating peptides including (arg)9 do not enter cells by directly passing through a lipid membrane but instead passively enter vesicles and live cells by inducing membrane multilamellarity and fusion. (Arg)9 also possesses antifungal and neuroprotective properties.
Holm et al (2012) Cell‐penetrating peptides as antifungals towards Malassezia sympodialis. Lett. Appl. Microbiol. 54 39 PMID: 22023266
Milani et al (2016) Poly-arginine peptides reduce infarct volume in a permanent middle cerebral artery rat stroke model. BMC Neurosci. 17(1) 19 doi:10.1186/s12868-016-0253-z
Allolio et al (2018) Arginine-rich cell-penetrating peptides induce membrane multilamellarity and subsequently enter via formation of a fusion pore. Proc. Natl. Acad. Sci. 115 (47) 11923 PMID: 30397112
Related areas
Technical Data
| Structure | H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH |
| CAS Number | 143413-47-2 |
| Molecular Weight | 1423.7 |
| Formula | C54H110N36O10 |
| Sequence | RRRRRRRRR |
| Modifications | None |
Solubility and Storage
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store frozen and desiccated in the dark |
Batch Specific Data
| Purity | ≥95% by HPLC |
| Safety Data Sheet | (Arg)9 MSDS_613a339a76f22.docx |
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