By using our website, you agree to our use of cookies. find out more.
-
Products
Pharmacology
Type
- News
- Custom services
- Ordering
- About Us
- Technical support
- Resources
-
Products
Pharmacology
Type
- News
- Custom services
- Ordering
- About Us
- Technical support
- Resources
Enzyme modulators
Enzymes are protein catalysts that cause a chemical change in another substance, with the molecules being transformed by enzymes known as substrates. Some enzymes act independently but others require the assistance of coenzymes in order to function correctly.
There are six main families of enzymes, oxidoreductases, which catalyze oxidation and reduction reactions, transferases, which transfer a functional group (such as a methyl or phosphate group), hydrolases, which catalyze the hydrolysis of various bonds, lyases, which cleave various bonds by means other than hydrolysis, isomerases, which catalyze isomerization changes within a single molecule, and ligases, which join two molecules together with covalent bonds. Enzymes are usually very selective as to which reactions they catalyze and the substrates that they act on. This selectivity is extremely important as enzymes serve a wide variety of key functions inside living organisms. Enzymes are essential for metabolic function and signal transduction.
Enzyme modulators categories
Copeland et al (2007) Targeting enzyme inhibitors in drug discovery, Exp. Opinion Ther. Targets 11(7) 967 PMID: 17614764
Cardinale et al (2010) Homodimeric Enzymes as Drug Targets. Curr. Med. Chem. Volume 17(9) 826 https://doi.org/10.2174/092986710790712156
Alexander et al (2019) The Concise Guide to Pharmacology 2019/20: Enzymes. Br J Pharmacol. 176 S1 S297 PMID: 31710719
Related Targets
Contact Information
To place an order, or for customer services, order processing or technical support please contact us on:
UK, Europe and RoW
Tel: (+44) 01392 422205Fax: (+44) 01392 279510
info@iscabiochemicals.com
USA and Canada
Tel: 610-994-1134
Toll Free: 855-FOCUS21 (855-362-8721)
Fax: 610-465-9100
France
CliniSciences
Tel : +33 9 77 40 09 09
Fax : +33 9 77 40 10 11
Orders and customer support : info@clinisciences.com
Germany, Switzerland, Austria
BIOZOL Diagnostics
Tel: +49 (089) 3799 666-6
Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: info@biozol.de
Italy
Labospace
Tel: +39 02 35980841
Fax +39 02 359808004
Orders: info@labospace.com
Spain and Portugal
Abyntek Biopharma
Tel: +34 94 404 80 80
Fax: +34 94 404 80 81
Orders: info@abyntek.com
BIOHUB INTERNATIONAL
上海起发实验试剂有限公司
Tel: +86-15921799099
Tel: +86-021-50724187
Fax: +86-021-50724961
Orders: sale3@78bio.com
India
BTL Biotechno Labs Pvt Ltd
Tel: +91-8860924629
07291852429
Orders, Technical and Customer support: info@biotechnolabs.com
Japan
Namiki Shoji Co.
Tel:+81-050-5527-9850
Fax:+81-3-3352-2196
email: globalbusiness1@namiki-s.co.jp
Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
Learn moreContact us
Isca Biochemicals
26 Hanover Road
Exeter
EX1 2TL
(+44) 01392 422205
info@iscabiochemicals.com