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Products
Pharmacology
Type
- News
- Custom services
- Ordering
- About Us
- Technical support
- Resources
Cancer
Cancer is a disease in which abnormal cells divide without control. These cells can create their own growth signals, avoid apoptosis and immune destruction, invade neighbouring tissues, undergo metastasis and angiogenesis and alter energy metabolism. Cancer genes are divided into oncogenes that promote cell growth, and suppressor genes that inhibit cell division and survival. Malignant transformation can occur through the formation of novel oncogenes, the over-expression of normal oncogenes, or the disabling of suppressor genes. Most human cancers (90–95% of cases) are due to genetic mutations from environmental factors, with the remainder caused by inherited genetic defects.
Cancer categories
Further reading
Dang et al (2017) Drugging the 'undruggable' cancer targets. Nat. Rev. Cancer 17 502 PMID: 28643779
Karki et al (2017) Inflammasomes and Cancer. Cancer Immunol. Res. 5(2) 94 PMID: 28093447
The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium (2020) Pan-cancer analysis of whole genomes Nature 578(7793) 82 PMID: 32025007
Contact Information
To place an order, or for customer services, order processing or technical support please contact us on:
UK, Europe and RoW
Tel: (+44) 01392 422205Fax: (+44) 01392 279510
info@iscabiochemicals.com
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Toll Free: 855-FOCUS21 (855-362-8721)
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CliniSciences
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Germany, Switzerland, Austria
BIOZOL Diagnostics
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Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: info@biozol.de
Italy
Labospace
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Fax +39 02 359808004
Orders: info@labospace.com
Spain and Portugal
Abyntek Biopharma
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Fax: +34 94 404 80 81
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BIOHUB INTERNATIONAL
上海起发实验试剂有限公司
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Tel: +86-021-50724187
Fax: +86-021-50724961
Orders: sale3@78bio.com
India
BTL Biotechno Labs Pvt Ltd
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07291852429
Orders, Technical and Customer support: info@biotechnolabs.com
Japan
Namiki Shoji Co.
Tel：+81-050-5527-9850
Fax：+81-3-3352-2196
email: globalbusiness1@namiki-s.co.jp
Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
Learn moreContact us
Isca Biochemicals
26 Hanover Road
Exeter
EX1 2TL
(+44) 01392 422205
info@iscabiochemicals.com