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Cancer

Cancer is a disease in which abnormal cells divide without control.  These cells can create their own growth signals, avoid apoptosis and immune destruction, invade neighbouring tissues, undergo metastasis and angiogenesis and alter energy metabolism.  Cancer genes are divided into oncogenes that promote cell growth, and suppressor genes that inhibit cell division and survival.  Malignant transformation can occur through the formation of novel oncogenes, the over-expression of normal oncogenes, or the disabling of suppressor genes.  Most human cancers (90–95% of cases) are due to genetic mutations from environmental factors, with the remainder caused by inherited genetic defects.

Further reading

Dang et al (2017) Drugging the 'undruggable' cancer targets. Nat. Rev. Cancer 17 502 PMID: 28643779

Karki et al (2017) Inflammasomes and Cancer. Cancer Immunol. Res. 5(2) 94 PMID: 28093447

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium (2020) Pan-cancer analysis of whole genomes Nature 578(7793) 82 PMID: 32025007



Contact Information

To place an order, or for customer services, order processing or technical support please contact us on:

UK, Europe and RoW
Tel: (+44) 01392 422205Fax: (+44) 01392 279510
[email protected]

USA and Canada

Tel: 610-994-1134

Toll Free: 855-FOCUS21 (855-362-8721)

Fax: 610-465-9100

[email protected] 


France

CliniSciences
Tel : +33 9 77 40 09 09
Fax :  +33 9 77 40 10 11
Orders and customer support : [email protected]


Germany, Switzerland, Austria

BIOZOL Diagnostics 

Tel: +49 (089) 3799 666-6

Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: [email protected]


Italy
Labospace
Tel: +39 02 35980841
Fax +39 02 359808004
Orders: [email protected]


Spain and Portugal
Abyntek Biopharma
Tel: +34 94 404 80 80

Fax: +34 94 404 80 81
Orders: [email protected]


China

BIOHUB INTERNATIONAL 

上海起发实验试剂有限公司

Tel: +86-15921799099

Tel: +86-021-50724187

Fax: +86-021-50724961

Orders: [email protected]

India
Biotechno Labs
Tel: +91-8860924629
07291852429
Orders, Technical and Customer support: [email protected]


Japan

Namiki Shoji Co.
Tel:+81-050-5527-9850
Fax:+81-3-3352-2196
email: [email protected]


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