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Products
Pharmacology
Type
- News
- Custom services
- Ordering
- About Us
- Technical support
- Resources
Transferases
Transferases are a large class of enzymes that catalyze the transfer of specific functional groups such as methyl, hydroxymethyl, formyl, glycosyl, acyl, alkyl, phosphate, and sulfate groups from one molecule to another. Transferases include methyltransferases and formyltransferases for transferring single-carbon groups – methyl (CH3) and formyl (CHO) groups respectively – and transaldolases for transferring a three carbon ketol group. Transferases are involved in hundreds of different biochemical pathways throughout biology, and are integral to some of lifes most important processes.
Peptides
| Cat No. | Product Name | Activity |
|---|---|---|
| EI-010 | BM30 | N-terminal methyltransferase1/2 (NTMT1/2) inhibitor |
| EI-020 | DC432 | N-terminal methyltransferase1/2 (NTMT1/2) inhibitor, cell permeable |
Small molecules
| Cat No. | Product Name | Activity |
|---|---|---|
| TR-010 | Etomoxir | Carnitine palmitoyltransferase inhibitor |
| KS-330 | Go 6983 | PKC inhibitor |
Further reading
Morton (1953) Transferase Activity of Hydrolytic Enzymes. Nature 172(4367) 65 PMID: 13072573
Dekker and Haisma (2009) Histone acetyl transferases as emerging drug targets. Drug Discov. Today 14 (19–20) 942 PMID: 19577000
Rask-Andersen et al (2011) Trends in the exploitation of novel drug targets. Nat. Rev. Drug Discov. 10 579 PMID: 21804595
Related Targets
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Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
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