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Dehydrogenases

Dehydrogenases are a subclass of oxidoreductases, ezymes which catalyze oxidation and reduction reactions. These enzymes fall into six categories: oxygenases, reductases, peroxidases, oxidases, hydroxylases, and dehydrogenases. Most oxidoreductase enzymes are dehydrogenases.  Oxidation-reduction reactions are essential to growth and survival of organisms, as the oxidation of organic molecules is an energy producing reaction which drives the synthesis of important energy molecules, such as ATP in glycolysis. For this reason, dehydrogenases have pivotal roles in metabolism.

Small molecules
Cat No. Product Name Activity
PI-050 N-Ethylmaleimide Sulfhydryl alkylating reagent

Further reading

Alberts et al (2002) Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. Catalysis and the Use of Energy by Cells.  ISBN-10: 0-8153-3218-1

Ying (2008) NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxid. Redox. Signal 2008 10(2) 179 PMID: 18020963.

Corpas and Barroso (2014) NADPH-generating dehydrogenases: their role in the mechanism of protection against nitro-oxidative stress induced by adverse environmental conditions. Front. Environ. Sci. 2 55 https://www.frontiersin.org/article/10.3389/fenvs.2014.00055

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