Search
0
Items
Select
Search
MENU
Select

Protein-sorting transpeptidase

Protein-sorting transpeptidases are enzymes, such as the sortase SrtA of Staphylococcus aureus, that cleave target proteins produced by the same cell, as part of a specialized pathway of protein targeting. Unlike other proteases, a protein-sorting transpeptidase transfers the N-terminal portion of the cleaved polypeptide into another molecule, such as a precursor of the peptidoglycan cell wall in Gram-positive bacteria. The term sortase is correctly reserved for the set of cysteine protease enzymes sortase A, sortase B, and members of additional classes, all of which share homology.
Fluorescent labelled peptides
Cat No. Product Name Activity
FP-020 5-FAM-LPETGG Sortase reagent
FP-010 Atto488-LPETGG Sortase reagent
FP-040 Atto550-LPETGG Sortase reagent
FP-030 Atto647N-LPETGG Sortase reagent

Further reading

Ton-That et al (1999) Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif.  96 (22) 12424 PMID: 10535938

Ton-That et al (2004) Protein sorting to the cell wall envelope of Gram-positive bacteria, Biochimica et Biophysica Acta (BBA) - Mol. Cell Res. 1694 1–3 269 PMID: 15546671

Jacobitz et al (2017). Sortase Transpeptidases: Structural Biology and Catalytic Mechanism. Advances in protein chemistry and structural biology. 109 223 PMID: 28683919

Contact Information

To place an order, or for customer services, order processing or technical support please contact us on:

UK, Europe and RoW
Tel: (+44) 01392 422205
Fax: (+44) 01392 279510
info@iscabiochemicals.com

USA and Canada

Tel: 610-994-1134

Toll Free: 855-FOCUS21 (855-362-8721)

Fax: 610-465-9100

sales@focusbiomolecules.com 


France

CliniSciences
Tel : +33 9 77 40 09 09
Fax :  +33 9 77 40 10 11
Orders and customer support : info@clinisciences.com


Germany, Switzerland, Austria

BIOZOL Diagnostics 

Tel: +49 (089) 3799 666-6

Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: info@biozol.de


Italy
Labospace
Tel: +39 02 35980841
Fax +39 02 359808004
Orders: info@labospace.com


Spain and Portugal
Abyntek Biopharma
Tel: +34 94 404 80 80

Fax: +34 94 404 80 81
Orders: info@abyntek.com


China

BIOHUB INTERNATIONAL 

上海起发实验试剂有限公司

Tel: +86-15921799099

Tel: +86-021-50724187

Fax: +86-021-50724961

Orders: sale3@78bio.com

India
BTL Biotechno Labs Pvt Ltd
Tel: +91-8860924629
07291852429
Orders, Technical and Customer support: info@biotechnolabs.com


Japan

Namiki Shoji Co.
Tel:+81-050-5527-9850
Fax:+81-3-3352-2196
email:  globalbusiness1@namiki-s.co.jp


All distributors >