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Products
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- Technical support
- Resources
Ziptide
Cat. No. SP-020
Structure:
H-Lys-Lys-Leu-Asn-Arg-Thr-Leu-Ser-Phe-Ala-Glu-Pro-Gly-OH
Activity:
Zipper interacting protein kinase (ZIPK) substrate
Ziptide is a substrate peptide used routinely as a substrate for zipper interacting protein kinase (ZIPK), also known as death-associated protein kinase 3 (DAPK3), a serine/threonine kinase that functions in programmed cell death. Ziptide can also be used as a substrate for the other serine/threonine-protein kinases BRSK2, and maternal embryonic leucine zipper kinase (MELK).
Witczak et al (2010) CaMKII regulates contraction- but not insulin-induced glucose uptake in mouse skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 298(6) E1150 PMID: 20215576
Yoshida and Goedert (2012) Phosphorylation of microtubule‐associated protein tau by AMPK‐related kinases. J. Neurochem. 120 165 PMID: 21985311
Related areas
Technical Data
| Structure | H-Lys-Lys-Leu-Asn-Arg-Thr-Leu-Ser-Phe-Ala-Glu-Pro-Gly-OH |
| Molecular Weight | 1460.69 |
| Formula | C65H109N19O19 |
| Sequence | KKLNRTLSFAEPG |
| Modifications | None |
Solubility and Storage
| Solubility | Soluble in water and physiological buffers |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
Batch Specific Data
| Purity | >95% by HPLC |
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Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
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