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Products
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[Ala97]-RII (81-99)
Cat. No. KS-100
Structure:
H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH
Activity:
Protein kinase A (PKA) substrate
[Ala97]-RII fragment (81-99) is a synthetic peptide fragment of the bovine cardiac cAMP-dependent protein kinase regulatory subunit (RII) and is a substrate for protein kinase A (PKA). [Ala97]-RII fragment (81-99) is phosphorylated at the serine residue using the catalytic subunit of protein kinase
Erdmann et al (2010) The Novel Calcineurin Inhibitor CN585 Has Potent Immunosuppressive Properties in Stimulated Human T Cells. J. Bio. Chem. 285 1888 PMID: 19923214
Related areas
Technical Data
| Structure | H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH |
| CAS Number | 113873-67-9 |
| Molecular Weight | 2113.0 |
| Formula | C92H150N28O29 |
| Sequence | DLDVPIPGRFDRRVSVAAE |
| Modifications | None |
Solubility and Storage
| Solubility | Soluble in dilute acid and physiological buffers |
| Appearance | Freeze dried solid |
| Storage | Store desiccated, frozen and in the dark |
Batch Specific Data
| Purity | >95% by HPLC |
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Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
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