The product has been added to the cart.
By using our website, you agree to our use of cookies. find out more.
-
Products
Pharmacology
Type
- News
- Custom services
- Ordering
- About Us
- Technical support
- Resources
-
Products
Pharmacology
Type
- News
- Custom services
- Ordering
- About Us
- Technical support
- Resources
Home
/
Products
/
7-Transmembrane receptors
/
Peptide receptors
/
Glucagon and related receptors
/
GIP_HUMAN[22–51]
GIP_HUMAN[22–51]
Cat. No. GL-040
Structure:
H-Glu-Lys-Lys-Glu-Gly-His-Phe-Ser-Ala-Leu-Pro-Ser-Leu-Pro-Val-Gly-Ser-His-Ala-Lys-Val-Ser-Ser-Pro-Gln-Pro-Arg-Gly-Pro-Arg-OH
Activity:
Endogenous proatherosclerotic peptide hormone
GIP_HUMAN[22–51] is a potent proatherosclerotic peptide hormone which has a common precursor with glucose-dependent insulinotropic polypeptide (GIP). Chronic infusion of GIP_HUMAN[22–51] into
ApoE−/− mice accelerates the development of aortic atherosclerotic lesions and it also increases the serum
concentrations of many inflammatory and proatherogenic proteins, and induces IκB-α degradation and nuclear translocation of
NF-κB in human vascular endothelial cells and macrophages. GIP_HUMAN[22–51 can also be labelled with 5-carboxyfluorescein and stable isotope labelled, please inquire.
Masaki et al (2021) GIP_HUMAN[22–51] is a new proatherogenic peptide identified by native plasma peptidomics. Sci Rep 11 14470 https://doi.org/10.1038/s41598-021-93862-w
Related data
All peptides >
All glucagon and related receptor modulators >
All cardiovascular research categories >
All immunology categories >
Technical Data
| Structure | H-Glu-Lys-Lys-Glu-Gly-His-Phe-Ser-Ala-Leu-Pro-Ser-Leu-Pro-Val-Gly-Ser-His-Ala-Lys-Val-Ser-Ser-Pro-Gln-Pro-Arg-Gly-Pro-Arg-OH |
| Molecular Weight | 3181.60 |
| Formula | C140H226N44O41 |
| Sequence | EKKEGHFSALPSLPVGSHAKVSSPQPRGPR |
| Modifications | None |
Solubility and Storage
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
Batch Specific Data
| Purity | >95% by hplc |
Contact Information
To place an order, or for customer services, order processing or technical support please contact us on:
UK, Europe and RoW
Tel: (+44) 01392 422205
Fax: (+44) 01392 279510
info@iscabiochemicals.com
USA and Canada
Tel: 610-994-1134
Toll Free: 855-FOCUS21 (855-362-8721)
Fax: 610-465-9100
France
CliniSciences
Tel : +33 9 77 40 09 09
Fax : +33 9 77 40 10 11
Orders and customer support : info@clinisciences.com
Germany, Switzerland, Austria
BIOZOL Diagnostics
Tel: +49 (089) 3799 666-6
Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: info@biozol.de
Italy
Labospace
Tel: +39 02 35980841
Fax +39 02 359808004
Orders: info@labospace.com
Spain and Portugal
Abyntek Biopharma
Tel: +34 94 404 80 80
Fax: +34 94 404 80 81
Orders: info@abyntek.com
BIOHUB INTERNATIONAL
上海起发实验试剂有限公司
Tel: +86-15921799099
Tel: +86-021-50724187
Fax: +86-021-50724961
Orders: sale3@78bio.com
India
BTL Biotechno Labs Pvt Ltd
Tel: +91-8860924629
07291852429
Orders, Technical and Customer support: info@biotechnolabs.com
Japan
Namiki Shoji Co.
Tel：+81-050-5527-9850
Fax：+81-3-3352-2196
email: globalbusiness1@namiki-s.co.jp
Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
Learn moreContact us
Isca Biochemicals
26 Hanover Road
Exeter
EX1 2TL
(+44) 01392 422205
info@iscabiochemicals.com
© 2025 Isca Biochemicals. All rights reserved.
Designed and developed by tocostudio