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Products
Pharmacology
Type
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- Technical support
- Resources
Parathyroid hormone (1 - 13) (human)
Cat. No. PH-030
Structure:
H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-OH
Other Names:
Tryptic peptide 1–13 PTH
Activity:
Amino acids 1-13 of the parathyroid hormone N-terminus
Parathyroid hormone (1 - 13) (human) is amino acids 1-13 of the N-terminus of parathyroid hormone and is a tryptic fragment sharing only 6 and 7 amino acids with the N-terminal tryptic peptides of parathyroid hormone related protein and parathyroid hormone (7–84) respectively. Parathyroid hormone (1 - 13) (human) has no substantial homology with any other trypsin digestion fragments of human proteins, making it a highly specific marker for full length parathyroid hormone (1–84).
Lopez et al (2010) Selected reaction monitoring-mass spectrometric immunoassay responsive to parathyroid hormone and related variants. Clin Chem. 56(2) 281 PMID: 20022981
Kumar et al (2010) Quantification of Serum 1–84 Parathyroid Hormone in Patients with Hyperparathyroidism by Immunocapture In Situ Digestion Liquid Chromatography–Tandem Mass Spectrometry, Clinical Chemistry, 56(2) 306 PMID: 20007860
Related areas
All peptides >
All parathyroid hormone receptor modulators >
All endocrinology research categories >
Technical Data
| Structure | H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-OH |
| Molecular Weight | 1455.69 |
| Formula | C62H106N18O20S |
| Sequence | SVSEIQLMHNLGK |
| Modifications | None |
Solubility and Storage
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
Batch Specific Data
| Purity | >95% by hplc |
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Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
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