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PACAP receptor peptide section
Published on May 4th 2021
PACAP (Pituitary adenylate cyclase-activating polypeptide) receptors are Gs-protein-coupled receptors referred to as PAC1, with an endogenous ligand, PACAP, that also activates the VIP receptors, VPAC1 and VPAC2. PAC1 receptors are predominantly expressed in the central nervous system, including the olfactory bulb, thalamus, hypothalamus, dentate gyrus and granule cells of the cerebellum as well as in the adrenal medulla and pancreas. PAC1 receptors are involved in daytime regulation of the biological clock, emotional control of behaviour, anxiolysis and control of adrenal medulla catecholamine release.
Isca have newly created a section for PACAP receptors and their ligands and we will be adding more key PACAP products to it over time. Please let us know if you want to see any particular favourite PACAP peptides in it.
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Isca Biochemicals
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(+44) 01392 422205
info@iscabiochemicals.com