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Products
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CXCL8 (54-72) scrambled control
Cat. No. IM-020
Structure:
Ac-Lys-Val-Arg-Glu-Lys-Asn-Glu-Lys-Trp-Phe-Val-Glu-Gln-Arg-Val-Ala-Leu-Asn-Ser-NH2
Other Names:
Peptide 3
Activity:
Scrambled version of CXCL8 (54-72) for use as a control
CXCL8 (54-72) scrambled control, also referred to as Peptide 3, is the scrambled peptide containing the wild-type amino acids of CXCL8 (54-72) in random order for use as a control. CXCL8 (54-72), is the C-terminal CXCL8 peptide fragment corresponding to the core CXCL8 - glycosaminoglycan (GAG) binding region which binds to GAG during neutrophil recruitment to reduce neutrophil adhesion and migration during the inflammatory response.
Martínez‐Burgo et al (2019), A C‐terminal CXCL 8 peptide based on chemokine–glycosaminoglycan interactions reduces neutrophil adhesion and migration during inflammation. Immunol. 157 173 PMID: 31013364
Related areas
All peptides >
All chemokine receptor modulators >
All adhesion molecule research categories >
All immunology research categories >
Technical Data
| Structure | Ac-Lys-Val-Arg-Glu-Lys-Asn-Glu-Lys-Trp-Phe-Val-Glu-Gln-Arg-Val-Ala-Leu-Asn-Ser-NH2 |
| Molecular Weight | 2401.75 |
| Formula | C107H173N33O30 |
| Sequence | Ac-KVREKNEKWFVEQRVALNS-NH2 |
| Modifications | N terminal acetylation, C terminal amidation |
Solubility and Storage
| Solubility | Soluble in physiological buffers including PBS (>1mg./mL). Soluble in DMSO as a stock |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
Batch Specific Data
| Purity | >95% by HPLC |
| Safety Data Sheet | CXCL8 (54-72) scrambled control MSDS_602bae5c81afa.pdf |
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Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
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