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WKYMVM

Cat. No. FR-030

Structure:

H-Trp-Lys-Tyr-Met-Val-Met-NH2

Other Names:

W-peptide

Activity:

Selective FPRL1 and FPRL2 receptor agonist

Price Qty
1 mg    $ 75.00

WKYMVM is a potent N-formyl peptide receptor agonist.  WKYMVM activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2.  WKYMVM also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and can activate NADPH oxidase

Christophe et al (2001) The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/Lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J.Biol.Chem. 276 21585 PMID: 11285256

Christophe et al (2002) Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1 /LXA4R, is not affected by lipoxin. Scand.J.Immunol. 56 470 PMID: 12410796

Karlsson et al (2007) Ability of monocyte-derived dendritic cells to secrete oxygen radicals in response to formyl peptide receptor family agonists compared to that of myeloid and plasmacytoid dendritic cells. Clin Vaccine Immunol. 14(3) 328 PMID: 17215332


Related areas

All peptides >
All formyl peptide receptor modulators >
All immunology research categories >


Technical Data

Structure H-Trp-Lys-Tyr-Met-Val-Met-NH2
CAS Number 187986-11-4
Molecular Weight 856.11
Formula C41H61N9O7S2
Sequence WKYMVM-NH2
Modifications C-terminal amide

Solubility and Storage

Solubility Soluble to 0.60 mg/ml in water
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark

Batch Specific Data

Purity >95% by hplc

Contact Information

To place an order, or for customer services, order processing or technical support please contact us on:

UK, Europe and RoW
Tel: (+44) 01392 422205
Fax: (+44) 01392 279510
info@iscabiochemicals.com

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CliniSciences
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Orders and customer support : info@clinisciences.com


Germany, Switzerland, Austria

BIOZOL Diagnostics 

Tel: +49 (089) 3799 666-6

Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: info@biozol.de


Italy
Labospace
Tel: +39 02 35980841
Fax +39 02 359808004
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Spain and Portugal
Abyntek Biopharma
Tel: +34 94 404 80 80

Fax: +34 94 404 80 81
Orders: info@abyntek.com


China

BIOHUB INTERNATIONAL 

上海起发实验试剂有限公司

Tel: +86-15921799099

Tel: +86-021-50724187

Fax: +86-021-50724961

Orders: sale3@78bio.com

India
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07291852429
Orders, Technical and Customer support: info@biotechnolabs.com


Japan

Namiki Shoji Co.
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