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OVA (257-264)

Cat. No. EP-010

Structure:

H-Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu-OH

Other Names:

Ovalbumin (257-264) (chicken)

Activity:

Antigenic ovalbumin peptide fraqment 
Price Qty
1 mg    £ 55.00

OVA (257-264) is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).  OVA(257-264) is an antigenic peptide and has been used to trigger T cell activation in immunology studies.  OVA (257-264) has been used to sensitize mice to generate an asthmatic model, in the stimulation of splenocytes and for treating dendritic cells to be used as a positive controls in cross-presentation studies.

Lipford et al (1993) Primary in vivo responses to ovalbumin. Probing the predictive value of the Kb binding motif. J. Immunology 150(4) 1212 PMID: 7679422

Wick and Pfeifer (1996), Major histocompatibility complex class I presentation of ovalbumin peptide 257–264 from exogenous sources: protein context influences the degree of TAP‐independent presentation. Eur. J. Immunol. 26 2790 PMID: 8921970

Karandikar et al (2019) New epitopes in ovalbumin provide insights for cancer neoepitopes. JCI Insight. 5(8)  e127882 PMID: 30869653


Related data

All epitopes >
All immunology research areas >


Technical Data

Structure H-Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu-OH
CAS Number 138831-86-4
Molecular Weight 963.13
Formula C45H74N10O13
Sequence SIINFEKL
Modifications None

Solubility and Storage

Solubility Soluble in any buffer > pH6
Appearance Freeze dried solid
Storage Store dry, frozen and in the dark

Batch Specific Data

Purity >95% by hplc

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