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Products
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OVA (257-264)
Cat. No. EP-010
Structure:
Other Names:
Activity:
OVA (257-264) is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). OVA(257-264) is an antigenic peptide and has been used to trigger T cell activation in immunology studies. OVA (257-264) has been used to sensitize mice to generate an asthmatic model, in the stimulation of splenocytes and for treating dendritic cells to be used as a positive controls in cross-presentation studies.
Lipford et al (1993) Primary in vivo responses to ovalbumin. Probing the predictive value of the Kb binding motif. J. Immunology 150(4) 1212 PMID: 7679422
Wick and Pfeifer (1996), Major histocompatibility complex class I presentation of ovalbumin peptide 257–264 from exogenous sources: protein context influences the degree of TAP‐independent presentation. Eur. J. Immunol. 26 2790 PMID: 8921970
Karandikar et al (2019) New epitopes in ovalbumin provide insights for cancer neoepitopes. JCI Insight. 5(8) e127882 PMID: 30869653
Related data
Technical Data
Structure | H-Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu-OH |
CAS Number | 138831-86-4 |
Molecular Weight | 963.13 |
Formula | C45H74N10O13 |
Sequence | SIINFEKL |
Modifications | None |
Solubility and Storage
Solubility | Soluble in any buffer > pH6 |
Appearance | Freeze dried solid |
Storage | Store dry, frozen and in the dark |
Batch Specific Data
Purity | >95% by hplc |
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Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
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