The product has been added to the cart.
By using our website, you agree to our use of cookies. find out more.
-
Products
Pharmacology
Type
- News
- Custom services
- Ordering
- About Us
- Technical support
- Resources
-
Products
Pharmacology
Type
- News
- Custom services
- Ordering
- About Us
- Technical support
- Resources
Bombesin
Cat. No. NR-150
Structure:
pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
Activity:
Endogenous mammalian neurotransmitter which activates bombesin receptors (BBR) 1, -2, and -3
Bombesin is a 14 amino acid endogenous mammalian neurotransmitter which activates three different G-protein-coupled receptors, bombesin receptor (BBR) 1, -2, and -3. Bombesin exhibits many biological effects including hormone release, stimulation of pancreatic enzyme secretion, inhibition of gastric emptying and modulation of gastric acid secretion. Bombesin also activates these receptors in the brain and together with cholecystokinin, it is the second major source of negative feedback signals that stop eating behaviour. Bombesin is also a tumour marker for small cell lung carcinoma, gastric cancer, pancreatic cancer, and neuroblastoma.
McCoy and Avery (1990) Bombesin: potential integrative peptide for feeding and satiety. Peptides 11 595 PMID: 2199952
Battey and Wada (1991) Two distinct subtypes for mammalian bombesin-like peptides. TiNS 14 524 PMID: 1726343
Zhang et al (2012) Evolution of Bombesin Conjugates for Targeted PET Imaging of Tumors. PLoS ONE 7(9) e44046 PMID: 23024746
Related areas
All peptides >
All bombesin receptor modulators >
All neuroscience research categories >
All endocrinology research categories >
All appetite regulation research categories >
All cancer research categories >
Technical Data
| Structure | pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 |
| CAS Number | 31362-50-2 |
| Molecular Weight | 1619.9 |
| Formula | C71H110N24O18S |
| Sequence | XQRLGNQWAVGHLM-NH2 |
| Modifications | X is pGlu, C terminal amide |
Solubility and Storage
| Solubility | Soluble in dilute acid |
| Appearance | Freeze dried solid |
| Storage | Store dark, frozen and desiccated |
Batch Specific Data
| Purity | >95% by HPLC |
Contact Information
To place an order, or for customer services, order processing or technical support please contact us on:
UK, Europe and RoW
Tel: (+44) 01392 422205
Fax: (+44) 01392 279510
info@iscabiochemicals.com
USA and Canada
Tel: 610-994-1134
Toll Free: 855-FOCUS21 (855-362-8721)
Fax: 610-465-9100
France
CliniSciences
Tel : +33 9 77 40 09 09
Fax : +33 9 77 40 10 11
Orders and customer support : info@clinisciences.com
Germany, Switzerland, Austria
BIOZOL Diagnostics
Tel: +49 (089) 3799 666-6
Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: info@biozol.de
Italy
Labospace
Tel: +39 02 35980841
Fax +39 02 359808004
Orders: info@labospace.com
Spain and Portugal
Abyntek Biopharma
Tel: +34 94 404 80 80
Fax: +34 94 404 80 81
Orders: info@abyntek.com
BIOHUB INTERNATIONAL
上海起发实验试剂有限公司
Tel: +86-15921799099
Tel: +86-021-50724187
Fax: +86-021-50724961
Orders: sale3@78bio.com
India
BTL Biotechno Labs Pvt Ltd
Tel: +91-8860924629
07291852429
Orders, Technical and Customer support: info@biotechnolabs.com
Japan
Namiki Shoji Co.
Tel：+81-050-5527-9850
Fax：+81-3-3352-2196
email: globalbusiness1@namiki-s.co.jp
Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
Learn moreContact us
Isca Biochemicals
26 Hanover Road
Exeter
EX1 2TL
(+44) 01392 422205
info@iscabiochemicals.com
© 2026 Isca Biochemicals. All rights reserved.
Designed and developed by tocostudio