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elf18
Cat. No. PL-020
Structure:
Ac-Ser-Lys-Glu-Lys-Phe-Glu-Arg-Thr-Lys-Pro-His-Val-Asn-Val-Gly-Thr-Ile-Gly-OH
Activity:
Inducer of defence responses
Elf18 is a peptide derived from the N-terminal of elongation factor thermo unstable (EF-Tu), a highly conserved protein in bacteria which is essential for the synthesis of new proteins, and also a pathogen-associated molecular pattern (PAMP) protein - elicitors of plant defences, recognised by pattern recognition receptors. Arabidopsis plants specifically recognise the N terminus of EF-Tu, and elf18 is fully active as a mimetic and inducer of defence responses. In leaves of Arabidopsis plants, elf18 induces an oxidative burst and biosynthesis of ethylene, and triggers resistance to subsequent infection with pathogenic bacteria.
Kunze et al (2004) The N terminus of bacterial elongation factor Tu elicits innate immunity in Arabidopsis plants. Plant Cell 16(12) 3496 PMID: 15548740
Zipfel et al (2006) Perception of the bacterial PAMP EF-Tu by the receptor EFR restricts Agrobacterium-mediated transformation. Cell 125(4) 749 PMID: 16713565
Seo et al (2017) ELF18-INDUCED LONG-NONCODING RNA Associates with Mediator to Enhance Expression of Innate Immune Response Genes in Arabidopsis. Plant Cell 29(5) 1024 PMID: 28400491
Related areas
Technical Data
| Structure | Ac-Ser-Lys-Glu-Lys-Phe-Glu-Arg-Thr-Lys-Pro-His-Val-Asn-Val-Gly-Thr-Ile-Gly-OH |
| CAS Number | 849352-44-9 |
| Molecular Weight | 2068.11 |
| Formula | C91H149N27O28 |
| Sequence | Ac-SKEKFERTKPHVNVGTIG |
| Modifications | N terminal is acetylated |
Solubility and Storage
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store dry, frozen and in the dark |
Batch Specific Data
| Purity | >95% by hplc |
| Certificate of Analysis | PL-020-1MG 0928-C0726 certificate of analysis_6679605112bfb.pdf |
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Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
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