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Products
Pharmacology
Type
- News
- Custom services
- Ordering
- About Us
- Technical support
- Resources
LL 37 (human) biotinylated
Cat. No. AM-003
Structure:
Biotin-Ahx- Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH
Activity:
N-terminally biotinylated version of the host defence peptide LL 37
LL 37 (human) biotinylated is the N-terminally biotinylated version of the host defence peptide LL 37. The biotin group is attached via a 6-carbon spacer, 6-aminohexanoic acid (Ahx). The presence of the biotin tag allows numerous biochemical and microbiological applications. We also offer unlabelled LL 37 (AM-001) and the carboxyfluoresceinated version of LL 37 (AM-004).
Nuding et al (2013) Gastric Antimicrobial Peptides Fail to Eradicate Helicobacter pylori Infection Due to Selective Induction and Resistance. PLoS ONE 8(9) e73867 PMID: 24040100
Related areas
Technical Data
| Structure | Biotin-Ahx- Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH |
| Molecular Weight | 4832.5 |
| Formula | C221H366N64O55S |
| Sequence | Biotin-Ahx-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES |
| Modifications | Biotin attched to the N terminal via a 6-aminohexanoic acid linker |
Solubility and Storage
| Solubility | Soluble in water |
| Appearance | Freeze dried solid |
| Storage | Store dark, frozen and desiccated. |
Batch Specific Data
| Purity | >95% by HPLC |
| Safety Data Sheet | LL 37 (human) biotinylated MSDS_602bef1a8d209.pdf |
Contact Information
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Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
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