How to dissolve peptides

Where possible we provide specific solubility instructions for dissolving peptides. If specific instructions are not available, the following guidelines can be used. Most peptides are soluble in distilled water. If they do not completely dissolve, the addition of 1.0 M acetic acid for basic peptides (those containing arginine, lysine or histidine) or 1.0 M ammonium hydroxide for acidic peptides (those containing aspartic acid or glutamine) may help. Solubilisation of extremely insoluble peptides can be assisted with 10% DMSO, although the use of DMSO as co-solvent may interfere with some biological assays. Sonication can also be a useful aid for solubilizing peptides. When solubilizing peptides, it is recommended that the peptide be dissolved to the highest possible concentration, and then diluted with water or buffer to the working concentration. The buffer should only be added when the peptide is completely solubilized as salts may cause aggregation

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Contact Information

To place an order, or for customer services, order processing or technical support please contact us on:

UK, Europe and RoW
Tel: (+44) 01392 422205Fax: (+44) 01392 279510
[email protected]

USA and Canada

Tel: 610-994-1134

Toll Free: 855-FOCUS21 (855-362-8721)

Fax: 610-465-9100

[email protected] 


Tel : +33 9 77 40 09 09
Fax :  +33 9 77 40 10 11
Orders and customer support : [email protected]

Germany, Switzerland, Austria

BIOZOL Diagnostics 

Tel: +49 (089) 3799 666-6

Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: [email protected]

Tel: +39 02 35980841
Fax +39 02 359808004
Orders: [email protected]

Spain and Portugal
Abyntek Biopharma
Tel: +34 94 404 80 80

Fax: +34 94 404 80 81
Orders: [email protected]




Tel: +86-15921799099

Tel: +86-021-50724187

Fax: +86-021-50724961

Orders: [email protected]

Biotechno Labs
Tel: +91-8860924629
Orders, Technical and Customer support: [email protected]


Namiki Shoji Co.
email: [email protected]

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