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Products
Pharmacology
Type
- News
- Custom services
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- About Us
- Technical support
- Resources
New range of PAR receptor ligands
Published on August 10th 2021
Protease-activated receptors (PARs, also known as thrombin receptors) are G-protein-coupled receptors which are activated by cleavage of their N-terminal domains by serine proteases. Cleavage produces a tethered peptide ligand, which influences transmembrane signaling. Four subtypes of receptors been cloned (PAR1-4). PAR1 is the most well characterized member of this receptor family and is activated by the endogenous serine protease thrombin. PAR1 activation has been implicated in cardiovascular diseases.
Isca now have all the key PAR ligands in one place. See and buy them here: PAR receptor ligands
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Isca Biochemicals
26 Hanover Road
Exeter
EX1 2TL
(+44) 01392 422205
info@iscabiochemicals.com