Substance P

NR-140-25MG 25mg 200.00 GBP
NR-140-5MG 5mg 50.00 GBP

Product specification

Sequence: H-RPKPQQFFGLM-NH2
MW: 1347.6
Purity: >95% by HPLC
Appearance: Freeze dried solid
Formula: C63H98N18O13S
CAS: 33507-63-0
Solubility Soluble in dilute acid
Long Term Storage: Store dark, frozen and desiccated
Miscellaneous/General:

Substance P, 33507-63-0, also known as neurokinin-1, is a widely distributed neuropeptide which functions as a neurotransmitter in sensory neurones of the spinal cord, stimulates mast cell degranulation and histamine release; stimulates proliferation and differentiation of lymphocytes and induces immunoglobulin synthesis. Substance P dysregualtion is associated with inflammatory diseases and obesity.

Product Literature References

Chen et al. Molecular Pain (2014) 10: 30

Miegueu et al. Am J Physiol. Gastrointest. Liver Physiol. (2013) 304: G420-G427