RW4

AM-152 1mg 125.00 GBP

Product specification

Sequence: H-RWRWRWRW-NH2
MW: 1386.6 Da
Purity: >95% by HPLC
Appearance: Freeze dried solid
Formula: C86H91N25O8
CAS:
Solubility Soluble in dilute acid
Long Term Storage: Store dry, dark and frozen
Miscellaneous/General:

This antifungal, antibaceterial cationic peptide integrates into the membrane of gram-positive bacterial causing delocalisation of peripheral membrane proteins, limiting cellular energy and undermining cell-wall integrity. The peptide has been shown to have enhanced activity when in combination with other peptide antimicrobial agents.

Product Literature References

Wenzel et al. PNAS (2014) 111(14): E1409-1418

Gopal et al. Int. J. Mol. Sci. (2012) 13: 15042-15053

Mohan et al. Clinical Microbiology and Infection (2014) 20(1): O39-O46