MOG (35-55) Rat

NR-020-0.5MG 0.5mg 65.00 GBP
NR-020-1MG 1mg 100.00 GBP

Product specification

Sequence: H-MEVGWYRSPFSRVVHLYRNGK-OH
MW: 2582.0
Purity: >95% by HPLC
Appearance: Freeze dried solid
Formula: C118H177N35O29S
CAS: 149635-73-4
Solubility Soluble in dilute acid
Long Term Storage: Store dark, frozen and desiccated
Miscellaneous/General:

MOG (35-55), 149635-73-4. Myelin Oligodendrocyte Glycoprotein is a transmembrane glycoprotein expressed at the surface of oligodendrocyte cells and on the outermost surface of the myelin sheath. MOG (35-55) is highly encephalitogenic, inducing strong T-cell and B-cell responses. Because MOG (35-55) injection produces relapsing-remitting neurologic disease with clinical, histopathologic and immune similarities to multiple sclerosis, MOG-induced demyelination may serve as a model for MS.

Product Literature References

Casella et al. Journal of Neuroinflammation (2016) 13: 139

Oliver et al. J. Immunology (2003) 171: 462-468