Mca-PLGL-Dap(Dnp)-AR-NH2

PS-010-1MG 1mg 125.00 GBP
PS-010-5MG 5mg 495.00 GBP

Product specification

Sequence: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2
MW: 1093.2
Purity: >95% by HPLC
Appearance: Freeze dried solid
Formula: C49H68N14O15
CAS: 140430-53-1
Solubility Soluble in DMSO
Long Term Storage: Store dark, frozen and desiccated
Miscellaneous/General:

Mca-PLGL-Dpa-AR-amide, CAS 140430-53-1, is a sensitive synthetic peptide FRET substrate for continuous assays and in situ determination of matrix metalloproteinase (MMP) activity. Protease cleavage at the -Gly-Leu- bond releases the highly fluorescent Mca group from the 2,4-dinitrophenyl quencher, resulting in an increase in fluorescence intensity.

Product Literature References

Lopez-elegrin et al. J. Biol. Chem. (2013) 288: 21279-21294

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