[Leu144, Arg147]-PLP (139-151)

NR-040-1MG 1mg 70.00 GBP
NR-040-5MG 5mg 240.00 GBP

Product specification

Sequence: H-HSLGKLLGRPDKF-OH
MW: 1467.7
Purity: >95% by HPLC
Appearance: Freeze dried solid
Formula: C67H110N20O17
CAS: 188859-65-6
Solubility Soluble in dilute acid
Long Term Storage: Store dark, frozen and desiccated
Miscellaneous/General:

[Leu144, Arg147]-PLP (139-151),188859-65-6,  is an analogue of PLP (139-151) [Cat NR-010] and acts as a T-cell receptor antagonist, preventing development of the autoimmune disease model Experimental Allergic Encephalomyelitis.

Product Literature References

Ruiz et al. J. Immunol. (1999) 162: 3336-3341

Potolicchio et al. J. Immunol. (2005) 175: 4935-4947