Histatin-5

AM-091-0.5MG 0.5mg 75.00 GBP
AM-091-1MG 1mg 130.00 GBP

Product specification

Sequence: H-DSHAKRHHGYKRKFHEKHHSHRGY-OH
MW: 3036.3
Purity: >95% by HPLC
Appearance: Freeze dried solid
Formula: C133H195N51O33
CAS: 104339-66-4
Solubility Soluble in dilute acid
Long Term Storage: Store dry, frozen and desiccated
Miscellaneous/General:

Histatin-5 is a 24 amino acid Histidine-rich cationic salivary peptide. Antifungal activity againstCandida albiacansandAspergillus fumigansindicate that this is an important component of the human oral nonimmune host defence system. Antifungal activity is caused by disruption to mitochondrial respiration through reactive oxygen species (ROS) production.

Product Literature References

Raj et al. J Biol. Chem. (1990) 265: 3898-3905

Khan et al. J. AIDS Clin. Res. (2013) 4(193)

Helmerhorst et al. PNAS (2001) 98(25): 14637-14642

Mochon A. B. and H. Liu PLOS Pathog. 4(10): e1000190